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"Evidence Matters" with Aaron Berger of UBC

Oct 14, 2025

In this wide ranging conversation with Aaron Berger of UBC, we cover:


  • are FDA disruptions affecting cancellation rates and ability to forecast new business

  • status of biotech funding (note- not much has changed on this front since July)

  • how would IRA and Medicare price negotiations to impact CRO business opportunities, if at all

  • quick primer on pipeline and book to bill definitions, and why we saw growing pipelines but shrinking win rates throughout much of this year

  • why I've started to place far less emphasis on book to bill in my analysis of how well a CRO is performing, and what I now place far more emphasis on

  • what if anything I'm hearing about consolidation or divestiture

  • what happened to the grand ambitions of large CROs acquiring significantly more sites?

  • why you're not seeing CROs acquire AI clinical tech companies (hint: show me the revenue)

  • what we're seeing in the CRO pricing environment, how to adapt, and what tactics can help you live with larger discounts

  • what discounting behavior I was seeing earlier this year (and this was recorded before at least 1 big CRO finally admitted publicly to huge discounting last quarter)

  • I become the host and ask Aaron what UBC is doing in terms of business development and proposal strategy to continually differentiate itself

  • how narrow does UBC get on those differentiators?

  • and how the hell do you get that all done in a 1-2 weeks RFP deadline?

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